The eastern part of the city, with its twenty thousand inhabitants, is a district with a promising future.

It is bordered to the west by Linkenheimer Allee, Audenauerring, and Kapellenstraße, and to the south by the new Kriegsstraße-Ost. The quality of life in the neighborhoods on both sides of Durlacher Allee has improved significantly in recent years following renovations. Between Durlacher Tor and the Oststadt Ring, the Hardtwald forest, and the Südstadt district, numerous cultural monuments enhance the charm and appeal of the area. The old architectural styles, alongside some newer buildings, contribute to the diverse character of the Oststadt. A vibrant and growing community of people living and working can be found here, unlike in any other district of Karlsruhe. Many small businesses are located on the ground floor, beneath the residential buildings, which are typical of the Oststadt, which has also developed into the heart of the technology region in recent years. The Oststadt was home to Gottesaue Palace in the 16th century, which was rebuilt between 1982 and 1989. Today, Gottesaue Palace houses the State University of Music. Other sights in Karlsruhe's eastern district include Gottesaue Palace, the Old Cemetery, the Karlsruhe Main Cemetery (the oldest German park cemetery), various Art Nouveau streets, the KIT Botanical Garden, the Old Slaughterhouse, and Hoepfner Castle.